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Closed MAD2 (C-MAD2) is selectively incorporated into the mitotic checkpoint complex (MCC)
The mitotic checkpoint is a specialized signal transduction pathway that monitors kinetochore-microtubule attachment to achieve faithful chromosome segregation. MAD2 is an evolutionarily conserved mitotic checkpoint protein that exists in open (O) and closed (C) conformations. The increase of intrac...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3266009/ https://ncbi.nlm.nih.gov/pubmed/22037211 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.10.21.17919 |
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