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Closed MAD2 (C-MAD2) is selectively incorporated into the mitotic checkpoint complex (MCC)

The mitotic checkpoint is a specialized signal transduction pathway that monitors kinetochore-microtubule attachment to achieve faithful chromosome segregation. MAD2 is an evolutionarily conserved mitotic checkpoint protein that exists in open (O) and closed (C) conformations. The increase of intrac...

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Bibliografiska uppgifter
Huvudupphovsmän: Tipton, Aaron R, Tipton, Michael, Yen, Tim, Liu, Song-Tao
Materialtyp: Artigo
Språk:Inglês
Publicerad: Landes Bioscience 2011
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266009/
https://ncbi.nlm.nih.gov/pubmed/22037211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.10.21.17919
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