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Mitotic slippage is determined by p31(comet) and the weakening of the spindle-assembly checkpoint
Mitotic slippage involves cells exiting mitosis without proper chromosome segregation. Although degradation of cyclin B1 during prolonged mitotic arrest is believed to trigger mitotic slippage, its upstream regulation remains obscure. Whether mitotic slippage is caused by APC/C(CDC20) activity that...
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| Publicado no: | Oncogene |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7098889/ https://ncbi.nlm.nih.gov/pubmed/32029899 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-020-1187-6 |
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