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Basic Helix-Loop-Helix Transcription Factor Twist1 Inhibits Transactivator Function of Master Chondrogenic Regulator Sox9
Canonical Wnt signaling strongly inhibits chondrogenesis. Previously, we identified Twist1 as a critical downstream mediator of Wnt in repression of chondrocyte differentiation. However, the mechanistic basis for the antichondrogenic activity of Twist1 has not heretofore been established. Here, we s...
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| Main Authors: | , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Biochemistry and Molecular Biology
2012
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3375531/ https://ncbi.nlm.nih.gov/pubmed/22532563 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.328567 |
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