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The helix-loop-helix transcription factor TWIST is dysregulated in myelodysplastic syndromes

Patients with low-grade myelodysplastic syndromes (MDS) show high levels of tumor necrosis factor α (TNFα) and up-regulation of apoptosis in the marrow. In contrast, marrow cells in advanced MDS are typically resistant to TNFα-induced apoptosis but are rendered apoptosis-sensitive on coculture with...

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Detalhes bibliográficos
Main Authors: Li, Xiang, Marcondes, A. Mario, Gooley, Theodore A., Deeg, H. Joachim
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2953837/
https://ncbi.nlm.nih.gov/pubmed/20562331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-09-242313
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