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The helix-loop-helix transcription factor TWIST is dysregulated in myelodysplastic syndromes
Patients with low-grade myelodysplastic syndromes (MDS) show high levels of tumor necrosis factor α (TNFα) and up-regulation of apoptosis in the marrow. In contrast, marrow cells in advanced MDS are typically resistant to TNFα-induced apoptosis but are rendered apoptosis-sensitive on coculture with...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society of Hematology
2010
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2953837/ https://ncbi.nlm.nih.gov/pubmed/20562331 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-09-242313 |
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