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Identification of DJ-1/PARK-7 as a determinant of stroma-dependent and TNF-α–induced apoptosis in MDS using mass spectrometry and phosphopeptide analysis
In patients with myelodysplastic syndromes (MDS), apoptosis in hematopoietic cells is up-regulated in low-grade disease, whereas advanced disease is characterized by apoptosis resistance. We have shown that marrow stroma–derived signals convey sensitivity to tumor-necrosis-factor alpha (TNF-α)–media...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2837333/ https://ncbi.nlm.nih.gov/pubmed/20061558 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-08-236992 |
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