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Stroma-dependent apoptosis in clonal hematopoietic precursors correlates with expression of PYCARD

The role of the marrow microenvironment in the pathophysiology of myelodysplastic syndromes (MDSs) remains controversial. Using stromal/hematopoietic cell cocultures, we investigated the effects of stroma-derived signals on apoptosis sensitivity in hematopoietic precursors. The leukemia-derived cell...

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Detalhes bibliográficos
Main Authors: Mhyre, Andrew J., Marcondes, A. Mario, Spaulding, Emily Y., Deeg, H. Joachim
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2628371/
https://ncbi.nlm.nih.gov/pubmed/18945969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-04-152686
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