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Bidentate and tridentate metal-ion coordination states within ternary complexes of RB69 DNA polymerase
Two divalent metal ions are required for primer-extension catalyzed by DNA polymerases. One metal ion brings the 3′-hydroxyl of the primer terminus and the α-phosphorus atom of incoming dNTP together for bond formation so that the catalytically relevant conformation of the triphosphate tail of the d...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Wiley Subscription Services, Inc., A Wiley Company
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3375444/ https://ncbi.nlm.nih.gov/pubmed/22238207 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2026 |
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