Evidence for a dynamically driven T cell signaling mechanism()

T cells use the αβ T cell receptor (TCR) to bind peptides presented by major histocompatibility complex proteins (pMHC) on antigen presenting cells. Formation of a TCR-pMHC complex initiates T cell signaling via a poorly understood process, potentially involving changes in oligomeric state, altered...

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Autores principales: Hawse, William F., Champion, Mathew M., Joyce, Michelle V., Hellman, Lance M., Hossain, Moushumi, Ryan, Veronica, Pierce, Brian G., Weng, Zhiping, Baker, Brian M.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3375328/
https://ncbi.nlm.nih.gov/pubmed/22611242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1200952
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