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Conditional Stat1 Ablation Reveals the Importance of Interferon Signaling for Immunity to Listeria monocytogenes Infection

Signal transducer and activator of transcription 1 (Stat1) is a key player in responses to interferons (IFN). Mutations of Stat1 cause severe immune deficiencies in humans and mice. Here we investigate the importance of Stat1 signaling for the innate and secondary immune response to the intracellula...

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Detalhes bibliográficos
Main Authors: Kernbauer, Elisabeth, Maier, Verena, Stoiber, Dagmar, Strobl, Birgit, Schneckenleithner, Christine, Sexl, Veronika, Reichart, Ursula, Reizis, Boris, Kalinke, Ulrich, Jamieson, Amanda, Müller, Mathias, Decker, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3375314/
https://ncbi.nlm.nih.gov/pubmed/22719255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002763
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