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Caspase Inhibitors of the P35 Family Are More Active When Purified from Yeast than Bacteria

Many insect viruses express caspase inhibitors of the P35 superfamily, which prevent defensive host apoptosis to enable viral propagation. The prototypical P35 family member, AcP35 from Autographa californica M nucleopolyhedrovirus, has been extensively studied. Bacterially purified AcP35 has been p...

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Detalhes bibliográficos
Main Authors: Brand, Ingo L., Civciristov, Srgjan, Taylor, Nicole L., Talbo, Gert H., Pantaki-Eimany, Delara, Levina, Vita, Clem, Rollie J., Perugini, Matthew A., Kvansakul, Marc, Hawkins, Christine J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3375223/
https://ncbi.nlm.nih.gov/pubmed/22720082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0039248
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