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Bisquinolinium compounds induce quadruplex-specific transcriptome changes in HeLa S3 cell lines
BACKGROUND: Guanosine rich sequences capable of forming G-quadruplex (G4) motifs are enriched near the gene transcription start site (TSS) in the human genome. When probed at the single gene level, G-quadruplex motifs residing in promoter regions show substantial effects on gene transcription. Moreo...
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| Main Authors: | , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
BioMed Central
2012
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3375199/ https://ncbi.nlm.nih.gov/pubmed/22414013 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-5-138 |
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