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β-III Spectrin Is Critical for Development of Purkinje Cell Dendritic Tree and Spine Morphogenesis
Mutations in the gene encoding β-III spectrin give rise to spinocerebellar ataxia type 5, a neurodegenerative disease characterized by progressive thinning of the molecular layer, loss of Purkinje cells and increasing motor deficits. A mouse lacking full-length β-III spectrin (β-III(−/−)) displays a...
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| Hoofdauteurs: | , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Society for Neuroscience
2011
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3374928/ https://ncbi.nlm.nih.gov/pubmed/22090485 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3332-11.2011 |
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