Specific immunization strategies against oxidized LDL: a novel way to reduce non-alcoholic steatohepatitis in mice

BACKGROUND: Non-alcoholic steatohepatitis (NASH) is characterized by hepatic lipid accumulation combined with inflammation, which can ultimately progress into cirrhosis. Recently, we demonstrated that deletion of scavenger receptors (SR) CD36 and SR-A in haematopoietic cells reduced hepatic inflamma...

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Main Authors: Bieghs, Veerle, van Gorp, Patrick J, Walenbergh, Sofie, Gijbels, Marion J, Verheyen, Fons, Buurman, Wim A, Briles, David E., Hofker, Marten H, Binder, Christoph J, Shiri-Sverdlov, Ronit
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3374908/
https://ncbi.nlm.nih.gov/pubmed/22334337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.25660
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