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Ectopic Expression of Neurogenin 2 Alone is Sufficient to Induce Differentiation of Embryonic Stem Cells into Mature Neurons

Recent studies show that combinations of defined key developmental transcription factors (TFs) can reprogram somatic cells to pluripotency or induce cell conversion of one somatic cell type to another. However, it is not clear if single genes can define a cell̀s identity and if the cell fate definin...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Thoma, Eva C., Wischmeyer, Erhard, Offen, Nils, Maurus, Katja, Sirén, Anna-Leena, Schartl, Manfred, Wagner, Toni U.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3374837/
https://ncbi.nlm.nih.gov/pubmed/22719915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0038651
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