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Nicotinamide alone accelerates the conversion of mouse embryonic stem cells into mature neuronal populations

INTRODUCTION: Vitamin B(3) has been shown to play an important role during embryogenesis. Specifically, there is growing evidence that nicotinamide, the biologically active form of vitamin B(3), plays a critical role as a morphogen in the differentiation of stem cells to mature cell phenotypes, incl...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Griffin, Síle M., Pickard, Mark R., Orme, Rowan P., Hawkins, Clive P., Williams, Adrian C., Fricker, Rosemary A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5560552/
https://ncbi.nlm.nih.gov/pubmed/28817722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0183358
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