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Pharmacokinetic evaluation and In Vitro–In Vivo Correlation (IVIVC) of novel methylene-substituted 3,3′ diindolylmethane (DIM)

PURPOSE: 3,3′-Diindolylmethane (DIM) is the major in vivo product of the acid-catalyzed oligomerization of indole-3-carbinol present in cruciferous vegetables. 1, 1-bis (3′-indolyl)-1-(p-substituted phenyl) methanes [C-substituted diindolylmethanes (C-DIMs)] are a new class of anticancer compounds d...

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Bibliografiske detaljer
Main Authors: Patel, Apurva R, Spencer, Shawn D, Chougule, Mahavir B, Safe, Stephen, Singh, Mandip
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3374645/
https://ncbi.nlm.nih.gov/pubmed/22342559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejps.2012.01.012
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