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Ring-substituted analogs of 3,3′-diindolylmethane (DIM) induce apoptosis and necrosis in androgen-dependent and –independent prostate cancer cells

We recently reported that novel ring-substituted analogs of 3,3′-diindolylmethane (ring-DIMs) have anti-androgenic and growth inhibitory effects in androgen-dependent prostate cancer cells. The objectives of this study were to confirm the ability of 4,4′- and 7,7′-dibromo- and dichloro-substituted r...

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Detalhes bibliográficos
Publicado no:Invest New Drugs
Main Authors: Goldberg, A. A., Titorenko, V. I., Beach, A., Abdelbaqi, K., Safe, S., Sanderson, J. T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4841686/
https://ncbi.nlm.nih.gov/pubmed/23709189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10637-013-9979-y
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