3,3′-Diindolylmethane (DIM) and its ring-substituted halogenated analogs (ring-DIMs) induce differential mechanisms of survival and death in androgen-dependent and –independent prostate cancer cells

We recently reported that novel ring-substituted analogs of 3,3′-diindolylmethane (ring-DIMs) induce apoptosis and necrosis in androgen-dependent and –independent prostate cancer cells. In this paper, we have focused on the mechanism(s) associated with ring-DIM-mediated cell death, and on identifyin...

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Detalhes bibliográficos
Publicado no:Genes Cancer
Main Authors: Goldberg, Alexander A., Draz, Hossam, Montes-Grajales, Diana, Olivero-Verbél, Jesus, Safe, Stephen H., Sanderson, J. Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4482247/
https://ncbi.nlm.nih.gov/pubmed/26124925
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