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Size Matters: Sequential Mutations in Tumorigenesis May Reflect the Stochastic Effect of Mutagen Target Sizes

We tallied the number of possible mutant amino acids in proteins thought to be inactivated early in tumorigenesis and in proteins thought to be inactivated late in tumorigenesis, respectively. Proteins thought to be inactivated early in tumorigenesis, on average, have a greater number of alternative...

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Detaylı Bibliyografya
Asıl Yazarlar: Long, Kimberly, Abuelenen, Toaa, Pava, Libia, Bastille, Maya, Blanck, George
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: SAGE Publications 2011
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3374629/
https://ncbi.nlm.nih.gov/pubmed/22701759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1947601911436200
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