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Size Matters: Sequential Mutations in Tumorigenesis May Reflect the Stochastic Effect of Mutagen Target Sizes
We tallied the number of possible mutant amino acids in proteins thought to be inactivated early in tumorigenesis and in proteins thought to be inactivated late in tumorigenesis, respectively. Proteins thought to be inactivated early in tumorigenesis, on average, have a greater number of alternative...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
SAGE Publications
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3374629/ https://ncbi.nlm.nih.gov/pubmed/22701759 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1947601911436200 |
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