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Size Matters: Sequential Mutations in Tumorigenesis May Reflect the Stochastic Effect of Mutagen Target Sizes

We tallied the number of possible mutant amino acids in proteins thought to be inactivated early in tumorigenesis and in proteins thought to be inactivated late in tumorigenesis, respectively. Proteins thought to be inactivated early in tumorigenesis, on average, have a greater number of alternative...

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Hlavní autoři: Long, Kimberly, Abuelenen, Toaa, Pava, Libia, Bastille, Maya, Blanck, George
Médium: Artigo
Jazyk:Inglês
Vydáno: SAGE Publications 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3374629/
https://ncbi.nlm.nih.gov/pubmed/22701759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1947601911436200
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