Inflammatory Bowel Diseases Phenotype, C. difficile and NOD2 Genotype Are Associated with Shifts in Human Ileum Associated Microbial Composition

We tested the hypothesis that Crohn’s disease (CD)-related genetic polymorphisms involved in host innate immunity are associated with shifts in human ileum–associated microbial composition in a cross-sectional analysis of human ileal samples. Sanger sequencing of the bacterial 16S ribosomal RNA (rRN...

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Hlavní autoři: Li, Ellen, Hamm, Christina M., Gulati, Ajay S., Sartor, R. Balfour, Chen, Hongyan, Wu, Xiao, Zhang, Tianyi, Rohlf, F. James, Zhu, Wei, Gu, Chi, Robertson, Charles E., Pace, Norman R., Boedeker, Edgar C., Harpaz, Noam, Yuan, Jeffrey, Weinstock, George M., Sodergren, Erica, Frank, Daniel N.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2012
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3374607/
https://ncbi.nlm.nih.gov/pubmed/22719818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0026284
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