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The transcription factor cyclic AMP–responsive element–binding protein H regulates triglyceride metabolism
Here we report that the transcription factor CREB-H is required for the maintenance of normal plasma triglyceride (TG) levels. CREB-H deficient mice displayed hypertriglyceridemia (HTG) secondary to inefficient TG clearance catalyzed by lipoprotein lipase (Lpl), partly due to defective expression of...
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| Hauptverfasser: | , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3374483/ https://ncbi.nlm.nih.gov/pubmed/21666694 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2347 |
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