The transcription factor cyclic AMP–responsive element–binding protein H regulates triglyceride metabolism

Here we report that the transcription factor CREB-H is required for the maintenance of normal plasma triglyceride (TG) levels. CREB-H deficient mice displayed hypertriglyceridemia (HTG) secondary to inefficient TG clearance catalyzed by lipoprotein lipase (Lpl), partly due to defective expression of...

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Autori principali: Lee, Jung Hoon, Giannikopoulos, Petros, Duncan, Stephen A., Wang, Jian, Johansen, Christopher T., Brown, Jonathan D., Plutzky, Jorge, Hegele, Robert A., Glimcher, Laurie H., Lee, Ann-Hwee
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3374483/
https://ncbi.nlm.nih.gov/pubmed/21666694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2347
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