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Clinical Pharmacogenetics Implementation Consortium Guidelines for HLA-B Genotype and Abacavir Dosing
Human leukocyte antigen B (HLA-B) is responsible for presenting peptides to immune cells and plays a critical role in normal immune recognition of pathogens. A variant allele, HLA-B★57:01, is associated with increased risk of a hypersensitivity reaction to the anti-HIV drug abacavir. In the absence...
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| Prif Awduron: | , , , , , |
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| Fformat: | Artigo |
| Iaith: | Inglês |
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Nature Publishing Group
2012
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| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3374459/ https://ncbi.nlm.nih.gov/pubmed/22378157 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/clpt.2011.355 |
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