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A Genomic Mechanism for Antagonism Between Retinoic Acid and Estrogen Signaling in Breast Cancer

Retinoic acid (RA) triggers growth-suppressive effects in tumor cells and therefore RA has and its synthetic analogs have great potential as anti-carcinogenic agent. RA effects are mediated by Retinoic Acid Receptors (RARs), which regulate gene expression in an RA-dependent manner. To define the gen...

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Hlavní autoři: Hua, Sujun, Kittler, Ralf, White, Kevin P.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3374131/
https://ncbi.nlm.nih.gov/pubmed/19563758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2009.04.043
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