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Footprint of Positive Selection in Treponema pallidum subsp. pallidum Genome Sequences Suggests Adaptive Microevolution of the Syphilis Pathogen

In the rabbit model of syphilis, infection phenotypes associated with the Nichols and Chicago strains of Treponema pallidum (T. pallidum), though similar, are not identical. Between these strains, significant differences are found in expression of, and antibody responses to some candidate virulence...

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Main Authors: Giacani, Lorenzo, Chattopadhyay, Sujay, Centurion-Lara, Arturo, Jeffrey, Brendan M., Le, Hoavan T., Molini, Barbara J., Lukehart, Sheila A., Sokurenko, Evgeni V., Rockey, Daniel D.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2012
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3373638/
https://ncbi.nlm.nih.gov/pubmed/22720110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0001698
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