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Genetic engineering of Treponema pallidum subsp. pallidum, the Syphilis Spirochete

Despite more than a century of research, genetic manipulation of Treponema pallidum subsp. pallidum (T. pallidum), the causative agent of syphilis, has not been successful. The lack of genetic engineering tools has severely limited understanding of the mechanisms behind T. pallidum success as a path...

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Dettagli Bibliografici
Pubblicato in:PLoS Pathog
Autori principali: Romeis, Emily, Tantalo, Lauren, Lieberman, Nicole, Phung, Quynh, Greninger, Alex, Giacani, Lorenzo
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8284648/
https://ncbi.nlm.nih.gov/pubmed/34228757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1009612
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