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Genetic engineering of Treponema pallidum subsp. pallidum, the Syphilis Spirochete

Despite more than a century of research, genetic manipulation of Treponema pallidum subsp. pallidum (T. pallidum), the causative agent of syphilis, has not been successful. The lack of genetic engineering tools has severely limited understanding of the mechanisms behind T. pallidum success as a path...

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Publicat a:PLoS Pathog
Autors principals: Romeis, Emily, Tantalo, Lauren, Lieberman, Nicole, Phung, Quynh, Greninger, Alex, Giacani, Lorenzo
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8284648/
https://ncbi.nlm.nih.gov/pubmed/34228757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1009612
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