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Genetic engineering of Treponema pallidum subsp. pallidum, the Syphilis Spirochete

Despite more than a century of research, genetic manipulation of Treponema pallidum subsp. pallidum (T. pallidum), the causative agent of syphilis, has not been successful. The lack of genetic engineering tools has severely limited understanding of the mechanisms behind T. pallidum success as a path...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:PLoS Pathog
Hauptverfasser: Romeis, Emily, Tantalo, Lauren, Lieberman, Nicole, Phung, Quynh, Greninger, Alex, Giacani, Lorenzo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8284648/
https://ncbi.nlm.nih.gov/pubmed/34228757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1009612
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