A BAX/BAK and Cyclophilin D-Independent Intrinsic Apoptosis Pathway

Most intrinsic death signals converge into the activation of pro-apoptotic BCL-2 family members BAX and BAK at the mitochondria, resulting in the release of cytochrome c and apoptosome activation. Chronic endoplasmic reticulum (ER) stress leads to apoptosis through the upregulation of a subset of pr...

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Detalhes bibliográficos
Main Authors: Zamorano, Sebastián, Rojas-Rivera, Diego, Lisbona, Fernanda, Parra, Valentina, Court, Felipe A., Villegas, Rosario, Cheng, Emily H., Korsmeyer, Stanley J., Lavandero, Sergio, Hetz, Claudio
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3373601/
https://ncbi.nlm.nih.gov/pubmed/22719850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0037782
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