Exposure to Candida albicans Polarizes a T-Cell Driven Arthritis Model towards Th17 Responses, Resulting in a More Destructive Arthritis

BACKGROUND: Fungal components have been shown very effective in generating Th17 responses. We investigated whether exposure to a minute amount of C. albicans in the arthritic joint altered the local cytokine environment, leading to enhanced Th17 expansion and resulting in a more destructive arthriti...

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Main Authors: Marijnissen, Renoud J., Koenders, Marije I., van de Veerdonk, Frank L., Dulos, John, Netea, Mihai G., Boots, Annemieke M.H., Joosten, Leo A.B., van den Berg, Wim B.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3373564/
https://ncbi.nlm.nih.gov/pubmed/22719976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0038889
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