Exposure to Candida albicans Polarizes a T-Cell Driven Arthritis Model towards Th17 Responses, Resulting in a More Destructive Arthritis

BACKGROUND: Fungal components have been shown very effective in generating Th17 responses. We investigated whether exposure to a minute amount of C. albicans in the arthritic joint altered the local cytokine environment, leading to enhanced Th17 expansion and resulting in a more destructive arthriti...

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Bibliographic Details
Main Authors:	Marijnissen, Renoud J., Koenders, Marije I., van de Veerdonk, Frank L., Dulos, John, Netea, Mihai G., Boots, Annemieke M.H., Joosten, Leo A.B., van den Berg, Wim B.
Format:	Artigo
Language:	Inglês
Published:	Public Library of Science 2012
Subjects:	Research Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3373564/ https://ncbi.nlm.nih.gov/pubmed/22719976 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0038889
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Exposure to Candida albicans Polarizes a T-Cell Driven Arthritis Model towards Th17 Responses, Resulting in a More Destructive Arthritis

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