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Control of progesterone receptor transcriptional synergy by SUMOylation and deSUMOylation

BACKGROUND: Covalent modification of nuclear receptors by the Small Ubiquitin-like Modifier (SUMO) is dynamically regulated by competing conjugation/deconjugation steps that modulate their overall transcriptional activity. SUMO conjugation of progesterone receptors (PRs) at the N-terminal lysine (K)...

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Autors principals: Abdel-Hafiz, Hany A, Horwitz, Kathryn B
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3373386/
https://ncbi.nlm.nih.gov/pubmed/22439847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2199-13-10
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