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Chylomicronemia mutations yield new insights into interactions between lipoprotein lipase and GPIHBP1
Lipoprotein lipase (LPL) is a 448-amino-acid head-to-tail dimeric enzyme that hydrolyzes triglycerides within capillaries. LPL is secreted by parenchymal cells into the interstitial spaces; it then binds to GPIHBP1 (glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1) on...
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| Hauptverfasser: | , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3373243/ https://ncbi.nlm.nih.gov/pubmed/22493000 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/dds127 |
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