Mutations in lipoprotein lipase that block binding to the endothelial cell transporter GPIHBP1

GPIHBP1, a glycosylphosphatidylinositol-anchored protein of capillary endothelial cells, shuttles lipoprotein lipase (LPL) from subendothelial spaces to the capillary lumen. An absence of GPIHBP1 prevents the entry of LPL into capillaries, blocking LPL-mediated triglyceride hydrolysis and leading to...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Voss, Constance V., Davies, Brandon S. J., Tat, Shelly, Gin, Peter, Fong, Loren G., Pelletier, Christopher, Mottler, Charlene D., Bensadoun, André, Beigneux, Anne P., Young, Stephen G.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2011
Assuntos:
Biological Sciences
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3093490/
https://ncbi.nlm.nih.gov/pubmed/21518912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1100992108
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares