Carregant...

Calsyntenin-1 mediates axonal transport of the amyloid precursor protein and regulates Aβ production

Understanding the mechanisms that control processing of the amyloid precursor protein (APP) to produce amyloid-β (Aβ) peptide represents a key area of Alzheimer's disease research. Here, we show that siRNA-mediated loss of calsyntenin-1 in cultured neurons alters APP processing to increase prod...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Vagnoni, Alessio, Perkinton, Michael S., Gray, Emma H., Francis, Paul T., Noble, Wendy, Miller, Christopher C.J.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3373235/
https://ncbi.nlm.nih.gov/pubmed/22434822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/dds109
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!