Wordt geladen...

Calsyntenin-1 mediates axonal transport of the amyloid precursor protein and regulates Aβ production

Understanding the mechanisms that control processing of the amyloid precursor protein (APP) to produce amyloid-β (Aβ) peptide represents a key area of Alzheimer's disease research. Here, we show that siRNA-mediated loss of calsyntenin-1 in cultured neurons alters APP processing to increase prod...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Vagnoni, Alessio, Perkinton, Michael S., Gray, Emma H., Francis, Paul T., Noble, Wendy, Miller, Christopher C.J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2012
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3373235/
https://ncbi.nlm.nih.gov/pubmed/22434822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/dds109
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!