Complement receptor 2/CD21(−) human naive B cells contain mostly autoreactive unresponsive clones

Complement receptor 2–negative (CR2/CD21(−)) B cells have been found enriched in patients with autoimmune diseases and in common variable immunodeficiency (CVID) patients who are prone to autoimmunity. However, the physiology of CD21(−/lo) B cells remains poorly characterized. We found that some rhe...

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Main Authors: Isnardi, Isabelle, Ng, Yen-Shing, Menard, Laurence, Meyers, Greta, Saadoun, David, Srdanovic, Iva, Samuels, Jonathan, Berman, Jessica, Buckner, Jane H., Cunningham-Rundles, Charlotte, Meffre, Eric
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2010
Teme:
Immunobiology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3373152/
https://ncbi.nlm.nih.gov/pubmed/20231422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-09-243071
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