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Inflammation-independent defective early B cell tolerance checkpoints in rheumatoid arthritis

OBJECTIVE: Treatment-naïve rheumatoid arthritis (RA) patients suffer from defective early B cell tolerance checkpoints and fail to remove developing autoreactive B cells. However, it is unclear if these B cell tolerance checkpoint defects are primary to the disease or the result of ongoing inflammat...

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Detalhes bibliográficos
Main Authors: Menard, Laurence, Samuels, Jonathan, Ng, Yen-Shing, Meffre, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3699182/
https://ncbi.nlm.nih.gov/pubmed/21538313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.30164
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