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Neutrophil arrest by LFA-1 activation

Lymphocyte function-associated antigen-1 (LFA-1) is a heterodimeric integrin consisting of α(L) (gene name, Itgal) and β(2) (gene name, Itgb2) subunits expressed in all leukocytes. LFA-1 is essential for neutrophil recruitment to inflamed tissue. Activation of LFA-1 by chemokines allows neutrophils...

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Bibliographic Details
Main Authors: Lefort, Craig T., Ley, Klaus
Format: Artigo
Language:Inglês
Published: Frontiers Research Foundation 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3373145/
https://ncbi.nlm.nih.gov/pubmed/22701459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2012.00157
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