A novel angiopoietin-derived peptide displays anti-angiogenic activity and inhibits tumour-induced and retinal neovascularization

BACKGROUND AND PURPOSE: Pathological angiogenesis is associated with various human diseases, such as cancer, autoimmune diseases and retinopathy. The angiopoietin (Ang)–Tie2 system plays critical roles in several steps of angiogenic remodelling. Here, we have investigated the anti-angiogenic effect...

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Bibliografiske detaljer
Main Authors:	Palmer, GM, Tiran, Z, Zhou, Z, Capozzi, ME, Park, W, Coletta, C, Pyriochou, A, Kliger, Y, Levy, O, Borukhov, I, Dewhirst, MW, Rotman, G, Penn, JS, Papapetropoulos, A
Format:	Artigo
Sprog:	Inglês
Udgivet:	Blackwell Publishing Ltd 2012
Fag:	Research Papers
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3372838/ https://ncbi.nlm.nih.gov/pubmed/21943108 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2011.01677.x
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A novel angiopoietin-derived peptide displays anti-angiogenic activity and inhibits tumour-induced and retinal neovascularization

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