Anti-angiogenic properties of a sulindac analogue

BACKGROUND AND PURPOSE: Angiopoietins (Ang) are crucial for new blood vessel formation and exert their effects by acting on the Tie2 receptor. We have recently described a sulindac analogue 2-((1E,Z)-1-benzylidene-5-bromo-2-methyl-1H-inden-3-yl)acetic acid; termed C-18 from now onwards) that inhibit...

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Detalhes bibliográficos
Main Authors: Pyriochou, A, Tsigkos, S, Vassilakopoulos, T, Cottin, T, Zhou, Z, Gourzoulidou, E, Roussos, C, Waldmann, H, Giannis, A, Papapetropoulos, A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2189991/
https://ncbi.nlm.nih.gov/pubmed/17965739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707534
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