A novel angiopoietin-derived peptide displays anti-angiogenic activity and inhibits tumour-induced and retinal neovascularization

BACKGROUND AND PURPOSE: Pathological angiogenesis is associated with various human diseases, such as cancer, autoimmune diseases and retinopathy. The angiopoietin (Ang)–Tie2 system plays critical roles in several steps of angiogenic remodelling. Here, we have investigated the anti-angiogenic effect...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Palmer, GM, Tiran, Z, Zhou, Z, Capozzi, ME, Park, W, Coletta, C, Pyriochou, A, Kliger, Y, Levy, O, Borukhov, I, Dewhirst, MW, Rotman, G, Penn, JS, Papapetropoulos, A
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Publishing Ltd 2012
Schlagworte:
Research Papers
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3372838/
https://ncbi.nlm.nih.gov/pubmed/21943108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2011.01677.x
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