TM-25659 enhances osteogenic differentiation and suppresses adipogenic differentiation by modulating the transcriptional co-activator TAZ

BACKGROUND AND PURPOSE: The transcriptional co-activator with PDZ-binding motif (TAZ) is characterized as a transcriptional modulator of mesenchymal stem cell differentiation into osteoblasts and adipocytes. Moreover, increased TAZ activity in the nucleus enhances osteoblast differentiation and supp...

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Bibliografiske detaljer
Main Authors:	Jang, EJ, Jeong, H, Kang, JO, Kim, NJ, Kim, MS, Choi, SH, Yoo, SE, Hong, JH, Bae, MA, Hwang, ES
Format:	Artigo
Sprog:	Inglês
Udgivet:	Blackwell Publishing Ltd 2012
Fag:	Research Papers
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3372739/ https://ncbi.nlm.nih.gov/pubmed/21913895 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2011.01664.x
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TM-25659 enhances osteogenic differentiation and suppresses adipogenic differentiation by modulating the transcriptional co-activator TAZ

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