TM-25659 enhances osteogenic differentiation and suppresses adipogenic differentiation by modulating the transcriptional co-activator TAZ

BACKGROUND AND PURPOSE: The transcriptional co-activator with PDZ-binding motif (TAZ) is characterized as a transcriptional modulator of mesenchymal stem cell differentiation into osteoblasts and adipocytes. Moreover, increased TAZ activity in the nucleus enhances osteoblast differentiation and supp...

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Bibliographic Details
Main Authors: Jang, EJ, Jeong, H, Kang, JO, Kim, NJ, Kim, MS, Choi, SH, Yoo, SE, Hong, JH, Bae, MA, Hwang, ES
Format: Artigo
Language:Inglês
Published: Blackwell Publishing Ltd 2012
Subjects:
Research Papers
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3372739/
https://ncbi.nlm.nih.gov/pubmed/21913895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2011.01664.x
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