Canonical Wnt signalling activates TAZ through PP1A during osteogenic differentiation

TAZ, a transcriptional modulator, has a key role in cell proliferation, differentiation and stem cell self-renewal. TAZ activity is regulated by several signalling pathways, including Hippo, GPCR and Wnt signalling, but the regulatory mechanisms of TAZ activation are not yet clearly understood. In t...

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Autori principali: Byun, M R, Hwang, J-H, Kim, A R, Kim, K M, Hwang, E S, Yaffe, M B, Hong, J-H
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2014
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Original Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4013522/
https://ncbi.nlm.nih.gov/pubmed/24510127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2014.8
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