Adenosine signaling promotes regeneration of pancreatic β-cells in vivo

Diabetes can be controlled with insulin injections, but a curative approach that restores the number of insulin-producing β-cells is still needed. Using a zebrafish model of diabetes, we screened ~7000 small molecules to identify enhancers of β-cell regeneration. The compounds we identified converge...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Andersson, Olov, Adams, Bruce A., Yoo, Daniel, Ellis, Gregory C., Gut, Philipp, Anderson, Ryan M., German, Michael S., Stainier, Didier Y. R.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2012
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3372708/
https://ncbi.nlm.nih.gov/pubmed/22608007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2012.04.018
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