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Suppression of Alk8-mediated Bmp signaling cell-autonomously induces pancreatic β-cells in zebrafish

Bmp signaling has been shown to regulate early aspects of pancreas development, but its role in endocrine, and especially β-cell, differentiation remains unclear. Taking advantage of the ability in zebrafish embryos to cell-autonomously modulate Bmp signaling in single cells, we examined how Bmp sig...

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Detalhes bibliográficos
Main Authors: Chung, Won-Suk, Andersson, Olov, Row, Richard, Kimelman, David, Stainier, Didier Y. R.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2824271/
https://ncbi.nlm.nih.gov/pubmed/20080554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0910205107
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