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Co-administration of morphine and oxycodone vaccines reduces the distribution of 6-monoacetylmorphine and oxycodone to brain in rats

Opioid conjugate vaccines have shown promise in animal models as a potential treatment for opioid addiction. Individual vaccines are quite specific and each targets only a limited number of structurally similar opioids. Since opioid users can switch or transition between opioids, we studied a bivale...

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Autors principals: Pravetoni, M, Raleigh, MD, Le Naour, M, Tucker, AM, Harmon, TM, Jones, JM, Birnbaum, AK, Portoghese, PS, Pentel, PR
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3372705/
https://ncbi.nlm.nih.gov/pubmed/22583811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2012.04.101
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