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Sirolimus modulates HIVAN phenotype through inhibition of epithelial mesenchymal transition

HIV-associated nephropathy (HIVAN) is characterized by proliferative phenotype in the form of collapsing glomerulopathy and microcystic dilatation of tubules. Recently, epithelial mesenchymal transition (EMT) of renal cells has been demonstrated to contribute to the pathogenesis of proliferative HIV...

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Autores principales: Yadav, Anju, Kumar, Dileep, Salhan, Divya, Rattanavich, Rungwasee, Maheshwari, Subani, Adabala, Madhuri, Ding, Guohua, Singhal, Pravin C.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3372700/
https://ncbi.nlm.nih.gov/pubmed/22579465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexmp.2012.04.021
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