Sirolimus modulates HIVAN phenotype through inhibition of epithelial mesenchymal transition

HIV-associated nephropathy (HIVAN) is characterized by proliferative phenotype in the form of collapsing glomerulopathy and microcystic dilatation of tubules. Recently, epithelial mesenchymal transition (EMT) of renal cells has been demonstrated to contribute to the pathogenesis of proliferative HIV...

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Detalhes bibliográficos
Main Authors: Yadav, Anju, Kumar, Dileep, Salhan, Divya, Rattanavich, Rungwasee, Maheshwari, Subani, Adabala, Madhuri, Ding, Guohua, Singhal, Pravin C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3372700/
https://ncbi.nlm.nih.gov/pubmed/22579465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexmp.2012.04.021
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